Q+A Hyaluronic Acid Facial Serum. A hydrating Hyaluronic Acid serum for healthy and plump skin. Works as a moisturiser for your face, Vegan Friendly, Fragrance Free, 30ml/1fl.oz

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Hyaluronic Acid Crosspolymer helps draw moisture into the skin and holds it safely in the upper layers of the skin to keep you looking fresh and hydrated. Polyglutamic Acid pairs perfectly with Hyaluronic Acid and helps draw even more moisture into the skin by forming a protective barrier that reduces moisture loss throughout the day - they are the ultimate pairing for dry and dehydrated skin. In addition, a unique Rice Bran extract delivers plenty of antioxidants and soothing Vitamin E for protection against environmental stressors and keeping your complexion feeling super soft. Cicek N, Yildiz N, Alpay H. Intravesical hyaluronic acid treatment in recurrent urinary tract infections in children with spina bifida and neurogenic bladder. Journal of Pediatric Urology. 2020;16(3):366.e1-366.e5. doi:10.1016/j.jpurol.2020.02.009 Gupta RC, Lall R, Srivastava A, Sinha A. Hyaluronic acid: molecular mechanisms and therapeutic trajectory. Frontiers in Veterinary Science. 2019;6. doi:10.3389/fvets.2019.00192 Yang YJ, Lee WY, Kim YJ, Hong YP. A meta-analysis of the efficacy of hyaluronic acid eye drops for the treatment of dry eye syndrome. Int J Environ Res Public Health. 2021;18(5):2383. doi:10.3390/ijerph18052383 Yao ZY, Qin J, Gong JS, et al. Versatile strategies for bioproduction of hyaluronic acid driven by synthetic biology. Carbohydrate Polymers. 2021;264:118015. doi:10.1016/j.carbpol.2021.118015

Colletti A, Cicero AFG. Nutraceutical approach to chronic osteoarthritis: from molecular research to clinical evidence. International Journal of Molecular Sciences. 2021;22(23):12920. doi:10.3390/ijms222312920 How to recycle: Remove the lid from the tube. Wash out the tube and dry. Both our lids and tubes are 100% recyclable so can be disposed of in your domestic recycling. Maheu E, Rannou F, Reginster JY. Efficacy and safety of hyaluronic acid in the management of osteoarthritis: evidence from real-life setting trials and surveys. Seminars in Arthritis and Rheumatism. 2016;45(4):S28-S33. doi:10.1016/j.semarthrit.2015.11.008 Soliman F, Ye L, Jiang W, Hargest R. Targeting hyaluronic acid and peritoneal dissemination in colorectal cancer. Clinical Colorectal Cancer. doi:10.1016/j.clcc.2021.11.008Chronic pain: A randomized, double-blind, placebo-controlled clinical study of 72 people taking 45 milliliters (3 tablespoons) of high molecular weight HA by mouth during the first two weeks of the study resulted in reduced pain and pain medication usage. Of note, during the last two weeks of the study, the dose was reduced to 30 milliliters (2 tablespoons), and no further decrease in chronic pain was observed. Hyaluronic Acid is a potent hydrator and natural moisturiser. Don’t let the word “acid” scare you: we produce it naturally in our own bodies too! Enhanced by a range of natural ingredients, Q+A Hyaluronic Acid Facial Serum will quench even the thirstiest skin. Di Cicco M, Peroni D, Sepich M, Tozzi MG, Comberiati P, Cutrera R. Hyaluronic acid for the treatment of airway diseases in children: little evidence for few indications. Pediatric Pulmonology. 2020;55(8):2156-2169. doi:10.1002/ppul.24901

Lugo JP, Saiyed ZM, Lane NE. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutrition Journal. 2015;15(1). doi:10.1186/s12937-016-0130-8 Majeed M, Majeed S, Narayanan NK, Nagabhushanam K. A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee. Phytotherapy research: PTR. 2019;33(5):1457-1468. doi:10.1002/ptr.6338 Cagnacci A, Barattini DF, Casolati E, Pecoroni A, Mangrella M, Patrascu LC. Polycarbophil vaginal moisturizing gel versus hyaluronic acid gel in women affected by vaginal dryness in late menopausal transition: a prospective randomized trial. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2022;270:239-245. doi:10.1016/j.ejogrb.2022.01.021 Jensen GS, Attridge VL, Lenninger MR, Benson KF. Oral intake of a liquid high-molecular-weight hyaluronan associated with relief of chronic pain and reduced use of pain medication: results of a randomized, placebo-controlled double-blind pilot study. Journal of Medicinal Food. 2015;18(1):95-101. doi:10.1089/jmf.2013.0174

Abdulkareem AA, Al Marah ZA, Abdulbaqi HR, Alshaeli AJ, Milward MR. A randomized double‐blind clinical trial to evaluate the efficacy of chlorhexidine, antioxidant, and hyaluronic acid mouthwashes in the management of biofilm‐induced gingivitis. International Journal of Dental Hygiene. 2020;18(3):268-277. doi:10.1111/idh.12432 Simental-Mendía M, Sánchez-García A, Vilchez-Cavazos F, Acosta-Olivo CA, Peña-Martínez VM, Simental-Mendía LE. Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials. Rheumatology International. 2018;38(8):1413-1428. doi:10.1007/s00296-018-4077-2

Urinary tract infections: A study conducted in 10 children aged 2 to 18 years with spina bifida and neurogenic bladder who performed clean intermittent catheterization (a technique for bladder drainage) showed that the instillation of 40 milligrams (mg) HA into the bladder weekly for four weeks then monthly for the following three months reduced symptomatic recurrent urinary tract infections. However, further multicenter randomized, controlled clinical trials with larger sample sizes and longer follow-ups are needed to confirm such promising results. Delivery is on a selected date, you can choose a delivery day of your choice, up to 10 days in advance (Excluding next day delivery. Postcode restrictions apply) Cancer: Hyaluronic acid has been shown to facilitate metastasis in colorectal cancer in laboratory models. However, it is unclear how this may translate into “real-life” settings. If you have a history of cancer, do not use hyaluronic acid supplements without consulting your healthcare provider. Osteoarthritis: In a randomized study comparing the effect of intra-articular (within the joint) HA injection to betamethasone injection, people with osteoarthritis of the thumb underwent one cycle of three injections (one per week) of 0.5 cubic centimeters (cm 3) of HA 5 milligrams (mg). Intra-articular HA injection requires a prescription and is given as a shot to your knee joint by a trained healthcare professional. Hafsa J, Chaouch MA, Charfeddine B, et al. Effect of ultrasonic degradation of hyaluronic acid extracted from rooster comb on antioxidant and antiglycation activities. Pharmaceutical Biology. 2016;55(1):156-163. doi:10.1080/13880209.2016.1232740Wang SJ, Wang YH, Huang LC. The effect of oral low molecular weight liquid hyaluronic acid combination with glucosamine and chondroitin on knee osteoarthritis patients with mild knee pain. Medicine. 2021;100(5):e24252. doi:10.1097/md.0000000000024252‌ Ibraheem W, Jedaiba WH, Alnami AM, et al. Efficacy of hyaluronic acid gel and spray in healing of extraction wound: a randomized controlled study. Eur Rev Med Pharmacol Sci. 2022;26(10):3444-3449. doi:10.26355/eurrev_202205_28838 Essendoubi M, Gobinet C, Reynaud R, Angiboust JF, Manfait M, Piot O. Human skin penetration of hyaluronic acid of different molecular weights as probed by Raman spectroscopy. Skin Research and Technology. 2015;22(1):55-62. doi:10.1111/srt.12228